Clinical Challenge: How would you address this complex revision TKA case?

Knee
Revision
Total knee replacement
Clinical Challenge: How would you address this complex revision TKA case?

This clinical challenge involves extensive periprosthetic tibial osteolysis following total knee arthroplasty. How would you approach reconstruction in this patient?

Dany Mouarbes
CH Perpignan, France
Clinical presentation
  • 74-year-old woman, independent and in good general health
  • Past medical hx: Atrial fibrillation (Eliquis) and hypertension (bisoprolol)
  • Bilateral primary TKR performed more than 15 years ago
  • Presented with several months of persistent medial-sided left knee pain
  • Patient requesting surgical intervention due to her persistent debilitating knee pain

Physical Examination

  • No knee effusion
  • Medial-sided pain and tenderness over the proximal tibia
  • Good ROM : full extension to 110°
  • No frontal or sagittal laxity 
     

Xray

Xray
Xray

Infection work-up

  • CRP/ESR neg
  • Bone scintigraphy: Non-avid osteolytic lesion beneath the medial tibial baseplate (granuloma?)
  • Radiolabeled leukocyte scintigraphy: No evidence of active infection
Infection work-up

Scanner

Extensive medial metaphyseal epiphyseal periprosthetic osteolysis with thinning of the cortex.

Extensive medial metaphyseal epiphyseal periprosthetic osteolysis with thinning of the cortex

MRI

Well-defined, oval-shaped lesion (74 × 34 mm) with subtle peripheral enhancement following contrast administration, suggestive of a granulomatous lesion.
No features of GCT.

Management

Diagnostic: Extensive periprosthetic osteolysis with possible granuloma/ aseptic loosening.

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